Polymorphism
Phenotype
Controls n=425a % (n)
DCM n=442b % (n)
OR (95 % CI)
p-value
IFN
-γ
AA
Low
31(134)
29(127)
1.0
TA
Intermediate
51 (215)
46 (202)
TT
High
18 (76)
25 (111)
1.54 [1.12-2.14]
0.009
MHC2TA
GG
Low
7 (28)
6 (25)
1.0
GA
Intermediate
28 (119)
34 (150)
AA
High
65 (277)
60 (267)
1.25 [0.95-1.64]
0.101
For calculation of OR, heterozygotes were coded as AA of IFN-γ and GG of MHC2TA, respectively.
a
n=424 for MHC2TA;
b
n=440 for IFN-γ
Table 2:
Genotype frequency in patients with idiopathic dilated cardiomyopathy (DCM) and control subjects.
