Gene (SNP) Genotype RA cases, no (%) Controls, no (%)
IFN-γ (+874, rs2430561) A/A
A/T
T/T
20 (29%)
37 (54%)
12 (17%)
40 (30%)
64 (48%)
29 (22%)
IL-1α (-899, rs1800587) C/C
T/C
T/T
36 (52%)
27 (39%)
6 (9%)
68 (51%)
53 (40%)
12 (9%)
IL-1α (+4845, rs17561) G/G
G/T
T/T
29 (42%)
32 (46%)
8 (11%)
66 (50%)
55 (41%)
12 (9%)
IL-1β (-31, rs1143627) T/T
T/C
C/C
22 (32%)
43 (62%)
4 (6%)
48 (36%)
71 (53%)
14 (11%)
IL-1β (-511, rs16944) C/C
T/C
T/T
17 (25%)
44 (63%)
8 (12%)
49 (37%)
70 (53%)
14 (10%)
IL-1β (+3953, rs1143634) C/C
T/C
T/T
38 (55%)
28 (41%)
3 (4%)
84 (63%)
39 (29%)
10 (8%)
IL-4 (-590, rs2243250) C/C
C/T
T/T
20 (29%)
45 (65%)
4 (6%)
81 (61%)
48 (36%)
4 (3%)
IL-6 (-174, rs1800795) G/G
G/C
C/C
31 (45%)
29 (42%)
9 (13%)
37 (28%)
68 (51%)
28 (21%)
IL-10 (-592, rs1800872) C/C
C/A
A/A
28 (41%)
33 (48%)
8 (12%)
84 (63%)
44 (33%)
5 (4%)
IL-10 (-819, rs1800871) C/C
C/T
T/T
37 (54%)
24 (35%)
8 (11%)
85 (64%)
43 (32%)
5 (4%)
IL-10 (-1082, rs1800896) G/G
G/A
A/A
12 (17%)
49 (71%)
8 (12%)
28 (21%)
70 (53%)
35 (26%)
IL-18 (-137, rs187238) G/G
G/C
C/C
26 (38%)
43 (62%)
0
70 (53%)
52 (39%)
11 (8%)
IL-18 (-607, rs1946518) C/C
C/A
A/A
28 (42%)
29 (41%)
12 (17%)
45 (34%)
64 (48%)
24 (18%)
TNFα (-238, rs361525) G/G
G/A
A/A
63 (91%)
6 (9%)
0
129 (97%)
4 (3%)
0
TNFα (-308, rs1800629) G/G
G/A
A/A
37 (54%)
32 (46%)
0
99 (74%)
34 (26%)
0
Table 2: Distribution of genotypes among patients with RA and healthy control group.