Figure 1: Upregulation of tubulin-a and HLA-DR-a expression in AE lesions. Tubulin-a and HLA-DR-a were stained by immunohistochemistry in the lesional (A, D), non-lesional skin (B, E) of the same AE patients and in healthy skin (C, F). Infiltrating CD3+ cells (G, H, J) reflect the degree of inflammation. Results obtained for one representative AE patient and one healthy control are shown. Isotype control staining for lesional skin (J), non lesional skin of the same patient (K), and skin of a healthy individual (L) is shown.