Figure 5: CHPV specific IgM and IgG level in sera of CHPV exposed mice The virus exposed and unexposed Swiss albino (SA) and nude mice were bled at different time points. The mice were infected with live CHPV through intra-cerebral route on 21st day post exposure (DPE). The CHPV specific IgM and IgG in the sera was detected by mouse IgM and IgG capture ELISA. The cut off values are calculated by Mean +3 SD of OD from virus unexposed control mice. All the nude mice were died after intra-cerebral infection.