Figure 2: Inhibition of caspase-9-induced processing of ICAD by Bcl-2D/A or Bcl-xLD/A. The indicated cell lines were treated with 10 nM of CID for 0 to 6 h, followed by Western blotting for ICAD. The antibody used here detects the long and short isoforms of ICAD (ICAD-L and ICAD-S, respectively). Arrows indicate the caspaseprocessed forms of ICAD. Results are representative of two experiments.