Gene/SNP |
Geno/All |
n cases |
n controls |
P |
OR (95%CI) |
BANK1 |
|
|
|
|
|
RS17266594 |
CC |
5 |
13 |
0.4 |
|
|
CT |
30 |
71 |
0.05 |
|
|
TT |
55 |
70 |
0.0182 |
1.89 (1.11-3.2) |
|
C |
40 |
97 |
0.028 |
|
|
T |
140 |
211 |
0.028 |
1.61 (1.05-2.46) |
RS3733197 |
AA |
2 |
11 |
0.084 |
|
|
AG |
31 |
74 |
0.0172 |
0.52 (0.3-0.89) |
|
GG |
59 |
65 |
0.00168 |
2.34 (1.37-3.99) |
|
A |
35 |
96 |
0.00181 |
|
|
G |
149 |
204 |
0.00181 |
2 (1.29-3.11) |
CD3Z |
|
|
|
|
|
RS1799704 |
AA |
54 |
91 |
0.67 |
|
|
AC |
27 |
63 |
0.13 |
|
|
CC |
9 |
5 |
0.0241 |
3.42 (1.11-10.55) |
|
A |
135 |
245 |
0.6 |
|
|
C |
45 |
73 |
0.6 |
|
RS2143302 |
CC |
29 |
30 |
0.0142 |
2.10 (1.16-3.81) |
|
CT |
34 |
81 |
0.0588 |
|
|
TT |
25 |
47 |
0.82 |
|
|
C |
92 |
141 |
0.1 |
|
|
T |
84 |
175 |
0.1 |
|
RS704848 |
CC |
41 |
48 |
0.02 |
1.89 (1.1-3.25) |
|
CG |
29 |
80 |
0.0034 |
0.44 (0.26-0.76) |
|
GG |
18 |
24 |
0.36 |
|
|
C |
111 |
176 |
0.26 |
|
|
G |
65 |
128 |
0.26 |
|
RS858545 |
AA |
22 |
19 |
0.0137 |
2.32 (1.18-4.56) |
|
AC |
34 |
78 |
0.06 |
|
|
CC |
35 |
60 |
0.97 |
|
|
A |
78 |
116 |
0.19 |
|
|
C |
104 |
198 |
0.19 |
|
IL2 |
|
|
|
0.97 |
|
RS11575812 |
AA |
59 |
74 |
0.006 |
2.11 (1.23-3.61) |
|
AG |
22 |
68 |
0.0064 |
0.42 (0.24-0.74) |
|
GG |
9 |
14 |
0.79 |
|
|
A |
140 |
216 |
0.041 |
1.56 (1.02-2.38) |
|
G |
40 |
96 |
0.041 |
|
IL2RA |
|
|
|
|
|
RS4147359 |
AA |
14 |
13 |
0.06 |
|
|
AG |
36 |
59 |
0.54 |
|
|
GG |
35 |
82 |
0.07 |
|
|
A |
64 |
85 |
0.023 |
1.58 (1.06-2.36) |
|
G |
106 |
223 |
0.023 |
|
IL2RB |
|
|
|
|
|
RS743776 |
CC |
9 |
5 |
0.029 |
3.29 (1.07-10.15) |
|
CT |
31 |
64 |
0.26 |
|
|
TT |
51 |
86 |
0.93 |
|
|
C |
49 |
74 |
0.45 |
|
|
T |
133 |
236 |
0.45 |
|
IL2RB |
|
|
|
|
|
RS84460 |
AA |
14 |
10 |
0.0127 |
2.88 (1.22-6.82) |
|
AG |
26 |
72 |
0.011 |
0.49 (0.28-0.86) |
|
GG |
43 |
70 |
0.4 |
|
|
A |
54 |
92 |
0.6 |
|
|
G |
112 |
212 |
0.6 |
|
IRF5 |
|
|
|
|
|
RS10954213 |
AA |
40 |
43 |
0.0098 |
2.06 (1.19-3.59) |
|
AG |
32 |
76 |
0.025 |
0.54 (0.31-0.93) |
|
GG |
14 |
26 |
0.75 |
|
|
A |
112 |
162 |
0.05 |
|
|
G |
60 |
128 |
0.05 |
|
RS2004640 |
GG |
16 |
36 |
0.357 |
|
|
GT |
37 |
78 |
0.214 |
|
|
TT |
35 |
41 |
0.0313 |
1.84 (1.05-3.20) |
|
G |
69 |
150 |
0.05 |
|
|
T |
107 |
160 |
0.05 |
|
RS2070197 |
CC |
7 |
2 |
0.0049 |
7.3 (1.48-36.05) |
|
CT |
22 |
27 |
0.084 |
|
|
TT |
48 |
119 |
0.0012 |
0.4 (0.22-0.75) |
|
C |
36 |
31 |
0.000264 |
2.61 (1.54-4.42) |
|
T |
118 |
265 |
0.000264 |
0.38 (0.23-0.65) |
JAK1 |
|
|
|
|
|
RS310201 |
AA |
47 |
78 |
0.66 |
|
|
AG |
30 |
71 |
0.074 |
|
|
GG |
13 |
9 |
1.99 x 10-2 |
2.80 (1.14-6.83) |
|
A |
124 |
227 |
0.49 |
|
|
G |
56 |
89 |
0.49 |
|
RS7528403 |
GG |
66 |
115 |
0.86 |
|
|
GT |
17 |
41 |
0.21 |
|
|
TT |
7 |
3 |
0.023 |
4.39 (1.1-17.41) |
|
G |
149 |
271 |
0.47 |
|
|
T |
31 |
47 |
0.47 |
|
PTPN6 |
|
|
|
|
|
RS759052 |
CC |
52 |
102 |
0.4 |
|
|
CT |
27 |
51 |
0.79 |
|
|
TT |
9 |
5 |
0.022 |
3.5 (1.13-10.75) |
|
C |
131 |
255 |
0.1 |
|
|
T |
45 |
61 |
0.1 |
|
STAT4 |
|
|
|
|
|
RS7574865 |
GG |
46 |
109 |
0.045 |
0.57 (0.32-0.99) |
|
GT |
28 |
44 |
0.312 |
|
|
TT |
7 |
3 |
0.0147 |
4.8 (1.21-19.19) |
|
G |
120 |
262 |
0.0097 |
0.55 (0.34-0.87) |
|
T |
42 |
50 |
0.0097 |
1.83 (1.15-2.92) |
TNFA |
|
|
|
|
|
RS1800629 |
AA |
9 |
6 |
0.0633 |
|
|
AG |
34 |
36 |
0.0239 |
1.9 (1.08-3.35) |
|
GG |
50 |
113 |
0.0021 |
0.43 (0.25-0.74) |
|
A |
52 |
48 |
0.0008 |
2.12 (1.36-3.3) |
|
G |
134 |
262 |
0.0008 |
0.62 (0.42-0.93) |
OR: Odds Ratio; CI: 95% Confidence Interval; Geno: Genotype; All: Allele |