Sl No

Virus Type

Antiviral Mechanism

Reference

1

Friend virus complex (FVC)

No direct effect on FVC infection but Lf decreases myelopoiesis in bone marrow and spleen

[53]

2

Hepatitis C virus (HCV)

Binds to envelope protein of HCV (E1 and E2) and prevents adsorption of HCV to target cells

[54]

3

Rotavirus

Prevents docking of virus to viral receptors on the target cells

[55]

4

Poliovirus

LF interferes with entry of poliovirus into the target cell

[56]

5

Respiratory syncytial virus (RSV)

Not been elucidated so far

[57]

6

Human immunodeficiency virus (HIV)

Lf binds to gp120 and prevents adsorption and entry of HIV

[58,59]

7

Herpes simplex virus (HSV)

LF inhibits adsorption of virus to the target cells

[60]

8

Cytomegalovirus

LF interferes with the entry of virus into the target cell

[59]