Genotype Patients n= 46 Controls n=144 OR IC (95%) p
Pre-menopausal women n (%) n (%)    
GG* 12 (25.5) 35 (24.3)    
GA 26 (26.3) 73 (50.7) 1.0 (0.47- 2.33) 0.92
AA 8 (17.4) 36 (25.0) 0.64 (0.23-1.77) 0.39
Allele frequencies        
G 50 (54.3) 143 (49.7)    
A 42 (45.7) 145 (50.3)   0.43
         
Post-menopausal women n=84 n=45    
GG* 25 (29.8) 13 (28.9)    
GA 45 (53.5) 22 (48.9) 1.0 (0.45-2.46) 0.88
AA 14 (16.6) 10 (22.2) 0.72 (0.25-2.06) 0.55
Allele frequencies        
G 95 (56.5) 48 (53.3)    
A 73 (43.5) 42 (46.6)   0.62
OR: Odds Ratio; CI: Confidence Interval.
Categorical variables were compared using the χ2 test
Table 3: Genotype distribution and allele frequencies of the LEP G-2548A polymorphism in control subjects and patients with breast cancer according to menopause status.