Figure 5: Anti-hnRNP A1 antibodies caused an increase in apoptosis and depletion of ATP levels. A. Cellular ATP levels are significantly reduced when SK-N-SH cells were exposed to anti-hnRNP A1 antibodies. B. Antibodies were not cytotoxic to the SK-N-SH cells (Percent cytotoxicity was normalized based on the numbers detected in untouched cells). C. In contrast to control antibodies, reduced levels of caspase 3/7 were seen at 48 and 72 hours after anti-hnRNP A1 antibodies were added to the media. Results were analyzed with two-way ANOVA with Bonferroni multiple comparison test.