|Table 1: Clinical course of EAE in WT, PD-L1-/- and PD-L2-/- mice*.|
bsignificant (p ≤ 0.05) as compared to PD-L1-/- Ctrl group
csignificant (p ≤ 0.05) as compared to PD-L1-/- E2 group
*Statistical evaluation of EAE disease course for WT and PDL1-/- and PD-L2-/- Control and E2-implanted mice, including the Cumulative Disease Index (CDI), through Day 24 post-immunization for the 2 experiments (n=3-4 mice/group/ experiment). The daily disease scores from pooled data and corresponding CDI data from each of the three independent experiments (mean ± SEM) are presented. Additional information for the experiments is shown in Figure 1.