The induction of EAE in rats and treatment with Metf and/or LOV or vehicle were as detailed in Figure 1 legend. Shown are the composite mean ± SEM of three to four samples/group analyzed in triplicate to determine the levels of IFN-γ (A), IL-17A (B), anti-MBP IgG1 (C), anti-MBP IgG2b (D) and anti- MBP IgG2a (E) in the sera of EAE rats on peak clinical day. Differences were statistical significance as described for Figure 1 legend.
