The induction of EAE in rats and treatment with Metf and/or LOV or vehicle were as detailed in Figure 1 legend. Shown are the composite mean ± SEM of three to four samples/group analyzed in triplicate to determine the levels of CNTF (A), BDNF (B), IGF-1(C) and LIF (D) mRNA transcripts in the SCs of EAE rats on 25th dpi. Shown is the composite mean ± SEM of three to four samples/group analyzed in triplicate to determine the level of CNTF (A) protein in the SCs of EAE rats on 25th dpi. Representative western blot (IB) depicts levels of different proteins in the SCs of EAE rats on 25th dpi. Differences were statistical significance as described for Figure 1 legend.
