Figure 7: Metf and LOV combination restricts neurodegeneration in the SCs of EAE rats.
The induction of EAE in rats and treatment with Metf and/orLOV or vehicle were as detailed in Figure 1 legend. Representative photographs depicts MBP (left panel) and SMI-31 (middle panel) in the lateral funiculi of the SCs of rats (n=6)/group on 25th dpi. Arrowhead depicts loss of myelin and axonal protein in the white matter. Sections were counter stained with Hoechst dye (right panel).