Figure 2: The Subtype proliferation with calpeptin compared to each other. A comparison of the proliferation of all the subtypes of Th cells responsive to MBP Ac1-8 as measured by 3H-thymidine uptake when stimulated with MBP Ac1-8 peptide in presence of various concentrations of the calpain inhibitor calpeptin. A. The various Th subtypes were potentiated by cytokines and antibodies in the media. Mean ± SEM (n=3). B. Comparison of the proliferation of Th1 biased cells with Th2 biased cells at each data point. C. Comparison of the proliferation of Th2 biased cells with Th17 biased cells at each data point. D. Comparison of the proliferation of Th1 biased cells with Th17 biased cells at each data point. Mean ± SEM (n=3). *, p<0.05 when compared between groups at the same treatment point.