Figure 1: (LPS+IFN-γ) and polyIC induce the production of NO in human primary fetal mixed glial cultures: Mixed glial cells preincubated with different concentrations of L-NIL and PTIO for 1 h under serum free conditions were stimulated either with 1 μg/ml of LPS and 6.25 mU/ml of IFN-γ or 100 μg/ml polyIC for 24 h and the nitrite concentrations were measured (B). Data are means ± S.D. of three different experiments. ap<0.01 vs. control, bp<0.001 vs. control, cp<0.01 vs. nitrite in (LPS+IFN-γ) treatment, dp<0.001 vs. nitrite in polyIC treatment.