Clinical Feature |
Score |
ANA or SMA |
|
≥ 1:40 |
+1 |
≥ 1:80 |
+2 |
LKM-1 ≥ 1:40 |
+2 |
SLA positive |
+2 |
Antibodies absent |
0 |
Serum globulin or IgG |
|
Above upper normal limit |
+1 |
>1.1 upper normal limit |
+2 |
Normal |
0 |
Hepatitis viral markers |
|
Positive |
0 |
Negative |
+2 |
Liver histology (evidence of hepatitis is a necessary condition) |
|
Compatible with AIH |
+1 |
Typical AIH |
+2 |
Incompatible with AIH |
0 |
Interpretation of aggregate scores*: |
|
Probable AIH |
≥ 6 |
Definite AIH |
≥ 7 |
*Addition of all antibodies, maximum +2 points.
IgG: Immunoglobulin G; ANA: Anti-nuclear Antibodies; SMA: Smooth Muscle
Antibodies; LKM-1: Type 1 Liver-kidney Microsomal Antibodies; SLA: Soluble Liver
Antigen antibodies |