Author Year Totalpatients Overlappatients Prevalence Diagnosticcriteria†
Boberg et al. [82] 1996 114 with PSC 2 definite 38 probable 2% 33% Original scoring system
Czaja [2] 1998 162 with AIH 0 0% Modified IAIHG scoring system
26 with PSC 14 54%
Van Buuren et al. [76] 2000 113 with PSC 9 8% Descriptive
9 definite 0 probable 8% Original scoring system
8 definite 1 probable 7% 1% Revised scoring system
Kaya et al. [81] 2000 211 with PSC 4 definite 40 probable 2% 19% Original scoring system
3 definite 13 probable 1% 6% Revised scoring system
Gheorghe et al. [48] 2004 82 with AIH 6 7% Revised scoring system/descriptive PSC
Floreani et al. [90] 2005 41 with PSC 7 17% Revised scoring system/Descriptive PSCand ERCP
Czaja [46] 2008 24 with PSC 2 definite 7 probable 8% 29% Revised scoring system
2 definite 3 probable 8% 13% Simplified scoring system
Chandok et al. [91] 2010 147 with PSC 0 definite 0 probable   0% Revised scoring system
0 definite 2 probable 0% 1% Simplified scoring system
Hunter et al. [92] 2011 118 with AIH 12* 10% Descriptive AIH/PSC cholestasis andMRC
Notes:* identified from 24 patients with cholestasis; †please see references for details on diagnostic criteria.
Table 5: Large studies reporting prevalence of AIH-PSC overlap syndrome.