Figure 3: Induction of PBMCs proliferation by cultured DCs. To test the allostimulatory activity, DCs of healthy donors (donors; n=24) and TB patients (TB; n=55), including PPD-reactive (PPD+; n=31) and PPD-anergic (PPD-; n=24) patients were cultured with allogeneic PBMCs at a stimulator/responder ratio of 1:10 for 5 days. Control cultures included PBMCs alone (-DC). The data are expressed as M±S.E. *-pU<0.05 vs healthy donors; #-pU<0.05 vs PPDreactive patients.