| |
|
Newton’s Classification |
| Cytokine |
Statistic |
0 (n=47) |
1, 2 and 3 (n=42) |
1 (n=27) |
2, 3 (n=15) |
| IFN-g |
Mean |
0.24 |
3.83 (P=0.0004) |
0.47 |
9.88 |
| |
SD |
1.39 |
11.9 |
1.39 |
18.71 |
| |
CV (%) |
590.9 |
310.8 |
298.9 |
189.4 |
| |
Median |
0.00 |
0.07 |
0.00 |
0.74 |
| |
Minimum |
0.0 |
0.0 |
0.0 |
0.0 |
| |
Maximum |
9.6 |
64.4 |
6.8 |
64.4 |
| IL-2 |
Mean |
0.22 |
0.42 (P=0.058) |
0.36 |
0.55 |
| |
SD |
0.40 |
0.54 |
0.49 |
0.63 |
| |
CV (%) |
180.5 |
127.9 |
136.5 |
115.5 |
| |
Median |
0.00 |
0.00 |
0.00 |
0.46 |
| |
Minimum |
0.0 |
0.0 |
0.0 |
0.0 |
| |
Maximum |
1.2 |
2.2 |
1.7 |
2.2 |
| IL-4 |
mean |
0.33 |
0.46 (P=0.139) |
0.52 |
0.34 |
| |
SD |
0.56 |
0.566 |
0.622 |
0.444 |
| |
CV (%) |
168.3 |
124.1 |
119.9 |
129.5 |
| |
Median |
0.00 |
0.16 |
0.00 |
0.32 |
| |
Minimum |
0.0 |
0.0 |
0.0 |
0.0 |
| |
Maximum |
2.0 |
1.6 |
1.6 |
1.4 |
| IL-5 |
Mean |
0.56 |
0.80 (P=0.0744) |
0.68 |
1.01 |
| |
SD |
0.76 |
0.74 |
0.77 |
0.640 |
| |
CV (%) |
136.3 |
92.4 |
113.6 |
63.3 |
| |
Median |
0.00 |
0.16 |
0.63 |
1.09 |
| |
Minimum |
0.0 |
0.0 |
0.0 |
0.0 |
| |
Maximum |
2.6 |
1.6 |
2.6 |
2.4 |
| IL-6 |
Mean |
3.48 |
28.32 (P<0.0001) |
9.16 |
62.82 |
| |
SD |
5.21 |
40.06 |
10.64 |
63.40 |
| |
CV (%) |
149.8 |
162.6 |
116.2 |
100.9 |
| |
Median |
2.08 |
8.63 |
5.49 |
37.67 |
| |
Minimum |
0.0 |
0.0 |
0.0 |
3.7 |
| |
Maximum |
30.5 |
215.7 |
41.9 |
215.7 |
| IL-10 |
Mean |
0.08 |
1.06 (P<0.0001) |
0.47 |
2.13 |
| |
SD |
0.16 |
2.14 |
0.92 |
3.15 |
| |
CV (%) |
204.9 |
200.8 |
195.7 |
147.4 |
| |
Median |
0.00 |
0.17 |
0.00 |
1.09 |
| |
Minimum |
0.0 |
0.0 |
0.0 |
0.0 |
| |
Maximum |
0.6 |
10.2 |
3.9 |
10.2 |
| IL-17a |
Mean |
1.02 |
8.35 (P=0.026) |
2.78 |
18.39 |
| |
SD |
2.37 |
18.45 |
4.67 |
28.07 |
| |
CV (%) |
233.1 |
220.9 |
168.3 |
152.7 |
| |
Median |
0.00 |
0.00 |
0.00 |
6.89 |
| |
Minimum |
0.0 |
0.0 |
0.0 |
0.0 |
| |
Maximum |
9.0 |
89.2 |
13.7 |
89.2 |
| IL-22 |
Mean |
9.90 |
76.70 (P=0.0004) |
33.39 |
154.65 |
| |
SD |
13.66 |
124.13 |
74.50 |
157.14 |
| |
CV (%) |
138.0 |
161.8 |
223.1 |
101.6 |
| |
Median |
0.00 |
24.72 |
7.81 |
91.11 |
| |
Minimum |
0.0 |
0.0 |
0.0 |
0.0 |
| |
Maximum |
39.3 |
411.4 |
321.8 |
411.4 |
| TGF-b1 |
Mean |
258.67 |
360.39(P<0.0001) (P<0.0001) |
321.37 |
430.64 |
| |
SD |
495.52 |
308.77 |
297.32 |
326.81 |
| |
CV (%) |
191.6 |
85.7 |
92.5 |
75.9 |
| |
Median |
186.89 |
280.11 |
273.48 |
343.90 |
| |
Minimum |
10.1 |
93.4 |
93.4 |
167.1 |
| |
|
|
|
|
|
| |
Maximum |
3537.0 |
1705.5 |
1705.5 |
1335.7 |
| TNF-a |
Mean |
0.02 |
0.69 (P=0.0009) |
0.61 |
0.84 |
| |
SD |
0.048 |
2.079 |
2.26 |
1.765 |
| |
CV (%) |
301.3 |
300.0 |
371.6 |
209.1 |
| |
Median |
0.00 |
0.00 |
0.00 |
0.15 |
| |
Minimum |
0.0 |
0.0 |
0.0 |
0.0 |
| |
Maximum |
0.2 |
11.6 |
11.6 |
6.1 |
CV (%): Coefficient of Variation.
P-value is based on the Wilcoxon Rank Sum test. |
