| |
Univariable
OR |
95% CI |
Multivariable- Adjusted*
OR |
95% CI |
| Sex |
|
|
|
|
| Female |
1.0 (ref.) |
- |
1.0 (ref.) |
- |
| Male |
0.76 |
0.69-0.84 |
0.73 |
0.66-0.81 |
| Age in years |
|
|
|
|
| 18-29 |
0.80 |
0.72-0.89 |
0.92 |
0.82-1.03 |
| 30-39 |
1.0 (ref.) |
- |
1.0 (ref) |
- |
| 40-49 |
1.10 |
0.99-1.23 |
1.00 |
0.89-1.12 |
| >50 |
1.23 |
1.11-1.36 |
0.99 |
0.89-1.11 |
| Year of ESRD onset |
|
|
|
|
| 1995-1998 |
0.79 |
0.70-0.88 |
0.77 |
0.69-0.87 |
| 1999-2001 |
0.98 |
0.88-1.09 |
0.96 |
0.86-1.08 |
| 2002-2004 |
1.09 |
0.99-1.20 |
1.05 |
0.94-1.16 |
| 2005-2008 |
1.0 (ref.) |
- |
1.0 (ref) |
- |
| Medical Insurance |
|
|
|
|
| Private |
1.0 (ref.) |
- |
1.0 (ref.) |
- |
| Medicaid |
0.73 |
0.67-0.81 |
0.84 |
0.75-0.94 |
| No insurance |
0.38 |
0.33-0.44 |
0.45 |
0.38-0.53 |
| Medicare |
1.03 |
0.92-1.16 |
1.07 |
0.95-1.22 |
| Race |
|
|
|
|
| White |
1.0 (ref.) |
- |
1.0 (ref) |
- |
| African American |
0.79 |
0.73-0.85 |
0.74 |
0.68-0.82 |
| Asian |
1.31 |
1.11-1.54 |
1.18 |
0.99-1.41 |
| Native American |
0.96 |
0.66-1.40 |
0.89 |
0.60-1.31 |
| Ethnicity |
|
|
|
|
| Hispanic |
0.91 |
0.82-1.00 |
0.87 |
0.77-0.98 |
| Region of Residence |
|
|
|
|
| Northeast |
1.0 (ref.) |
- |
1.0 (ref) |
- |
| West |
0.80 |
0.71-0.91 |
0.72 |
0.64-0.83 |
| South |
0.71 |
0.64-0.79 |
0.78 |
0.70-0.88 |
| Midwest |
0.82 |
0.73-0.93 |
0.82 |
0.72-0.93 |
| Employment at ESRD onset |
|
|
|
|
| Employed |
1.0 (ref.) |
- |
1.0 (ref) |
- |
| Unemployed |
0.73 |
0.66-0.80 |
0.85 |
0.76-0.94 |
| BMI (kg/m2) |
|
|
|
|
| Underweight BMI<18 |
1.10 |
0.95-1.27 |
1.16 |
1.00-1.35 |
| 18 -25 |
1.0 (ref.) |
- |
1.0 (ref) |
- |
| Overweight/Obesity BMI>25 |
0.88 |
0.82-0.95 |
0.87 |
0.80-0.94 |
| Serum albumin (mg/dl) |
|
|
|
|
| ≤2.5 |
0.70 |
0.64-0.77 |
0.73 |
0.66-0.81 |
| 2.6-3.2 |
1.0 (ref) |
- |
1.0 (ref) |
- |
| ≥3.3 |
1.43 |
1.31-1.56 |
1.35 |
1.23-1.48 |
| Hemoglobin (mg/dl) |
|
|
|
|
| ≤8.5 |
0.75 |
0.68-0.83 |
0.80 |
0.72-0.88 |
| 8.6-10 |
1.0 (ref) |
- |
1.0 (ref) |
- |
| ≥10 |
1.22 |
1.12-1.34 |
1.13 |
1.03-1.24 |
| eGFR (ml/min) |
|
|
|
|
| ≤0.0 |
0.88 |
0.80-0.97 |
1.00 |
0.90-1.10 |
| 5.0-10.0 |
1.0 (ref) |
- |
1.0 (ref) |
- |
| ≥10.0 |
0.89 |
0.81-0.97 |
0.86 |
0.78-0.95 |
| Comorbidities |
|
|
|
|
| Hypertension |
1.40 |
1.28-1.53 |
1.40 |
1.27-1.54 |
| Coronary artery disease |
1.40 |
1.21-1.62 |
1.36 |
1.17-1.60 |
| Peripheral vascular disease |
1.31 |
1.07-1.59 |
1.31 |
1.06-1.61 |
| Diabetes mellitus |
0.98 |
0.86-1.12 |
1.08 |
0.94-1.23 |
| Congestive heart failure |
0.85 |
0.76-0.94 |
0.88 |
0.79-0.99 |
| Chronic pulmonary obstructive disease |
0.94 |
0.74-1.20 |
0.90 |
0.70-1.17 |
| Cerebrovascular accident |
1.16 |
0.99-1.37 |
1.10 |
0.93-1.31 |
| Current smoking |
0.83 |
0.68-1.00 |
0.83 |
0.67-1.02 |
| IV Drug abuse |
0.42 |
0.25-0.71 |
0.56 |
0.32-0.97 |
| Cancer |
1.28 |
0.96-1.72 |
1.22 |
0.90-1.66 |
eGFR: Estimated Glomerular Filtration Rate; ESA: Erythropoiesis-Stimulating Agent; LN: Lupus Nephritis; ESRD: End-Stage Renal Disease; OR: Odds Ratio.
*Multivariable analysis adjusted for all variables in the table. |
