Extra-intestinal manifestations Healthy controls (n=21) cases with UC (n=38) Cases with CD (n=16) P (Fisher's exact) comparing:
N % N % N % UC to Healthy CD to Healthy UC to CD
Arthralgia 0 0.0 14 36.8 4 25.0 <0.001 0.028 0.53[NS]
Dermatol. problems 0 0.0 6 15.8 0 0.0 0.08[NS]* ** 0.16[NS]
Positive test results
s.HLA-G 0 0.0 18 47.4 16 100.0 <0.001 <0.001 <0.001
Anti-Elastase 0 0.0 24 63.2 16 100.0 <0.001 <0.001 0.005
Anti-Cathepsin-G 0 0.0 21 55.3 4 25.0 <0.001 0.028 0.07[NS]
Anti-lysozyme 2 9.5 2 5.3 7 43.8 0.61[NS] 0.024 0.002
[NS]: Not Significant; **Incomparable.
Table 2: Distribution of extra-intestinal manifestations and prevalence of serological markers among IBD patients and healthy control members.