The positive test Sensitivity Specificity Accuracy PPV at pretest probability= NPV at pretest probability=10% 50% 90% s.HLA-G 100.0 52.6 66.7 67.9 95.0 100.0 Anti-Elastase 100.0 36.8 55.6 61.3 93.4 100.0 Anti-Cathepsin-G 43.8 94.7 79.6 89.3 98.7 93.8

Table 7: Validity parameters for selected serum antibodies when used as test to diagnose CD differentiating it to UC.