Figure 3: Receiver operating characteristic curves (ROC) of uMCP-1 and serological markers for the diagnosis of LN activity in SLE patients. The AUC was 0.82 (95% CI: 0.73-0.91: p=0.001), the symbol (+) represents the best cut-off value (4,247 pg/mL) with a sensitivity and a specificity of 0.87 and 0.61 respectively. The AUC for anti dsDNA Ab titres was 0.50 (p=0.95) and that for serum C3 and serum C4 were 0.37 (p=0.50) and 0.43 (p=0.26). These later were lower than that for uMCP-1.