| Parameters |
Active LN n=47 |
Inactive LN n=53 |
p value |
| Haemoglobin (NR14.0-17.0 g/dL) |
12.2 (8.6-16.6) |
12.3 (8.5-15.6) |
0.57 |
| Total WBC (NR 4.0-10.0 × 109/L) |
7.7 ± 3.6 |
7.1 ± 2.65 |
0.45 |
| Platelet count (NR 150-400) |
234 ± 112 |
256 ± 83.5 |
0.19 |
| Serum albumin (NR 35-50 g/L) |
37.78 ± 5.54 |
41.88 ± 3.59 |
<0.001 |
| Serum creatinine (NR 44-80 μmol/L) |
69 (33-252) |
63 (41-158) |
0.29 |
| eGFR (ml/min/1.73 m2) |
93.61 ± 46.01 |
99.75 ± 31.54 |
0.43 |
| uPCI (NR<200 mg/mmol) |
1100 (100-5100) |
200 (100-500) |
<0.001 |
| uMCP-1 ( (pg/mg creatinine) |
9317.5 (548.3-40170) |
3682 (0-23.86) |
<0.001 |
| Serum C3 (NR 79-152 mg/dL) |
100.5 ± 36.39 |
109.62 ± 39.94 |
0.24 |
| Serum C4 (NR 16-38 mg/dL) |
21.46 ±12.82 |
22.94 ± 11 |
0.54 |
| Anti dsDNA Ab titres (NR<30 IU) |
35.18 (1.73-195.97) |
24.24 (0.81- 279.21) |
0.84 |
| SLEDAI-2K (global: 0-105) |
8 (0-18) |
2 (0-10) |
<0.001 |
| SLEDAI-2K (renal: 0-16) |
4 (0-16) |
0 (0-3.5) |
<0.001 |
| SLEDAI-2K (extra-renal: 0-89) |
2 (0-10) |
2 (0-10) |
0.66 |
| Medications, no. (%) |
|
|
|
| - Prednisolone |
43 (91.5) |
52 (98.1) |
0.12 |
| - Cyclophosphamide |
8 (17) |
0 (0) |
0.002 |
| - Mychophenolic acid |
12 (25.5) |
10 (18.9) |
0.42 |
| - Cyclosporine/Tacrolimus |
19 (40.4) |
11 (20.8) |
0.03 |
| - Azathioprine |
12 (25.5) |
24 (45.3) |
0.04 |
| - Hydroxychloroquine |
20 (42.6) |
22 (41.5) |
0.91 |
| - Renin Angiotension System Blockers (ACEI/ARB/Spironolactone) |
29 (61.7) |
39 (73.6) |
0.11 |
Values are in median (interquartile range) or mean (standard deviation). [p
values were calculated by Mann-Whitney U test or Independent sample T test];
LN: Lupus Nephritis; WBC: White Blood Cell count; eGFR: Estimated Glomerular
Filtration Rate; uPCI: Urine Protein Creatinine Index; SLEDAI-2K: Systemic Lupus
Erythematosus Disease Activity Index-2K; anti-dsDNA: Anti Double Stranded DNA;
C3: Complement 3; C4: Complement 4.