Figure 2: Production of IL-10 by monocytes (A) and monocytederived immature (B) and mature (C) dendritic cells in FMF patients. Peripheral blood monocytes were incubated with medium alone (NT) or 10 ng/ml IL-4 or 100 ng/ml LPS or 2 μg/ml colchicine for 3 days. Monocyte-derived iDCs and mDCs, described in section Material and methods, stimulated with 100 ng/ml LPS or 2 μg/ml colchicine for 24 h and IL-10 concentration in cell free supernatants determined by ELISA. All data represent means ± SEM (error bars) and are significantly different comparing FMF with ND (* Pt<0.05) or comparing with NT (# Pp<0.05).