Figure 1: Typical MRIs of SLE with NMO. (A) T2-weighted axial images indicatehyperintense lesions in the hypothalamus (B) and periaqueductal, which highly express the aquaporin 4 molecule. (C) A T2-weighted sagittal image of the spinal cord indicates the swelling and alongitudinal lesion. (D) A T2-weighted axial image of the spinal cord indicates a hyperintense lesion in the central parts of the spinal cord.