|
Baseline |
2 months |
4 months |
|
|
|
95% CI |
|
|
95% CI |
|
|
95% CI |
Variables |
AUC |
p |
LB |
UB |
AUC |
p |
LB |
UB |
AUC |
p |
LB |
UB |
uNGAL |
0.83 |
0.001 |
0.74 |
0.92 |
0.70 |
0.002 |
0.59 |
0.81 |
0.79 |
<0.001 |
0.68 |
0.90 |
Serum albumin |
0.23 |
0.004 |
0.13 |
0.33 |
0.24 |
<0.001 |
0.14 |
0.35 |
0.23 |
<0.001 |
0.12 |
0.34 |
Serum creatinine |
0.59 |
0.14 |
0.46 |
0.72 |
0.57 |
0.25 |
0.43 |
0.71 |
0.70 |
0.003 |
0.57 |
0.84 |
eGFR |
0.40 |
0.15 |
0.27 |
0.53 |
0.40 |
0.16 |
0.27 |
0.54 |
0.29 |
0.004 |
0.16 |
0.43 |
Anti dsDNA Ab titres |
0.48 |
0.78 |
0.35 |
0.61 |
0.47 |
0.74 |
0.34 |
0.61 |
0.53 |
0.71 |
0.35 |
0.70 |
Serum C3 |
0.39 |
0.09 |
0.26 |
0.51 |
0.46 |
0.56 |
0.33 |
0.58 |
0.39 |
0.18 |
0.25 |
0.53 |
Serum C4 |
0.43 |
0.35 |
0.30 |
0.56 |
0.42 |
0.27 |
0.30 |
0.55 |
0.46 |
0.67 |
0.30 |
0.62 |
Haematuria |
0.62 |
0.08 |
0.48 |
0.76 |
0.54 |
0.51 |
0.41 |
0.67 |
0.62 |
0.08 |
0.48 |
0.76 |
Proteinuria (uPCI) |
0.94 |
<0.001 |
0.90 |
0.99 |
0.92 |
<0.001 |
0.85 |
0.99 |
0.88 |
<0.001 |
0.78 |
0.97 |
SLEDAI-2K (renal score) |
0.96 |
<0.001 |
0.90 |
1 |
0.84 |
<0.001 |
0.75 |
0.92 |
0.84 |
<0.001 |
0.75 |
0.93 |
AUC: Area Under the Curve; CI: Confidence Interval; LB: Lower Bound; UB: Upper Bound; C3: Complement 3; C4: Complement 4; uPCI: Urine Protein Creatinine Index; SLEDAI-2K: Systemic Lupus Erythematosus Disease Activity Index-2K |