Figure 3

Figure 3: NK cell lytic proteins in CFS/ME and control groups. Granzyme B expression was significantly reduced in CD56^dimCD16⁺ and CD56-CD16+ NK cells from CFS/ME patients in comparison to the controls (A). CD56^dimCD16⁺ and CD56-CD16+ NK cells from the CFS/ME and control groups expressed significantly increased amounts of Granzyme B (A) and perforin (B) in comparison to CD56^brightCD16^-/dim NK cells. Granzyme A expression was significantly increased in CD56^dimCD16⁺ NK cells compared to CD56^brightCD16^-/dim NK cells in both the groups (C). Data is presented as mean ± standard error of the mean (*P<0.05, **P<0.01, ***P<0.001 and ****P<0.0001).