Analyte |
M2 (pg/mL) |
M2 + VSL#3 (pg/mL) |
Fold-Change |
Mean ΔCCS |
95% CI |
Mean ΔCCS |
95% CI |
IL-1β * |
0.12 |
-0.12, 0.36 |
71.17 |
70.92, 71.42 |
593.08 |
IL-1Ra |
187.00 |
159.56, 214.44 |
490.00 |
462.56, 517.44 |
2.62 |
IL-2 |
11.15 |
9.48, 12.82 |
0.75 |
-1.31, 2.81 |
0.07 |
IL-6 * |
3.15 |
0.90, 5.40 |
1813.15 |
1621.56, 2004.74 |
575.60 |
IL-7 |
2.55 |
0.49, 4.61 |
62.60 |
51.23, 73.97 |
24.55 |
IL-8 |
-23.70 |
-49.77, 2.37 |
8367.00 |
8341.52, 8392.48 |
354.04 |
IL-9 |
0.60 |
0.50, 0.70 |
50.78 |
48.67, 52.88 |
84.63 |
IL-10 |
60.70 |
44.43, 76.97 |
9718.39 |
9701.73, 9735.05 |
160.11 |
IL-12p40 |
4.30 |
3.12, 5.48 |
545.15 |
498.01, 592.29 |
126.78 |
IL-12p70 |
2.90 |
2.90, 2.90 |
24.65 |
23.96, 25.34 |
8.50 |
IL-13 |
6.75 |
4.30, 3.12 |
21.15 |
12.82, 29.48 |
3.13 |
IL-15 |
9.05 |
3.07, 15.03 |
24.65 |
24.36, 24.94 |
2.72 |
EGF |
1.35 |
1.25, 1.45 |
12.80 |
12.41, 13.19 |
9.48 |
Eotaxin |
1.40 |
1.20 1.60 |
26.45 |
23.61, 29.29 |
18.89 |
FGF-2 |
4.75 |
3.67, 5.83 |
19.35 |
16.51, 22.19 |
4.07 |
Fractalkaline# |
96.00 |
92.08, 99.92 |
237.50 |
207.12, 267.88 |
2.47 |
G-CSF * |
23.60 |
14.19, 33.01 |
2134.85 |
2058.31, 2211.39 |
90.46 |
GRO |
16.60 |
10.52, 22.68 |
4591.80 |
3891.49, 5292.11 |
276.61 |
IFN-α2 |
10.45 |
9.18, 11.72 |
39.50 |
37.93, 41.07 |
3.78 |
MCP-3 |
276.30 |
176.93, 375.67 |
45.65 |
45.16, 46.14 |
0.17 |
MIP-1α |
20.65 |
13.89, 27.41 |
309.55 |
300.04, 319.06 |
14.99 |
MIP-1β |
91.70 |
45.44, 137.96 |
980.80 |
770.30, 1191.30 |
10.70 |
TGF-α |
33.00 |
32.22, 33.78 |
302.85 |
302.56, 303.14 |
9.18 |
TNF-α |
17.15 |
2.35, 31.95 |
3378.05 |
3004.77, 3751.33 |
196.97 |
VEGF |
65.80 |
56.98, 74.62 |
7630.30 |
7455.66, 7804.94 |
115.96 |
* Change seen in all macrophage types; # Change seen in this macrophage type only; Cytokine levels for days 8 and 11 are shown in Supplemental Table 2; Levels for IL-4 were above the detection limit at both time points and are therefore not reported |