Prion inoculum Mice Incubation time (day, SD) Transmission rate iCJD case 1 Tg 40h 181 ± 3 8/8 iCJD case 2 Tg 40h 170 ± 7 8/8 sCJD case 1 Tg 40h 185 ± 5 8/8 SCJD case 2 Tg 40h 185 ± 3 8/8

Table 1: Prion transmission in transgenic mice.