| Author |
No of IBD patients (in clinical remission) |
Results |
| Tibble [11] |
43 CD
37 UC |
Basal FCC ≥ 250 mg/g predicts a 13-fold increased risk for relapse within a year |
| Costa [5] |
38 CD
41 UC |
Basal FCC ≥ 150 mg/g is highly predictive for a relapse in the next year |
| Garcia-Sanchez, [39] |
69 CD
69 UC |
CD: basal FCC ≥ 200 mg/g predicts a 4-fold increased risk for relapse in the next year
UC: basal FCC ≥ 120 mg/g predicts a 6-fold increased risk for relapse |
| Laharie, [40] |
65 CD |
No showed correlations between FCC and risk for relapse
|
| De Vos, [41] |
87 UC |
Basal FCC ≥ 300 mg/g correlate with relapse in the next year. Two consecutive value >300 mg/g with an 1 month interval is the best predictor of flare |
| Lasson, [42] |
69 UC |
Basal FCC >262 mg/g has an increased risk of relapse during the first 3 years after onset |
| Mao, [43] |
318 UC
354 CD |
The pooled sensitivity and specificity of FC to predict relapse of quiescent IBD was 78% and 73%, respectively, with comparable results between UC and CD. |
IBD: Inflammatory Bowel Disease; UC: Ulcerative Colitis; CD: Crohn’s Disease; FCC: Fecal Calprotectin Concentration