Factor |
UC |
CD |
smoking |
--- |
+++ |
appendectomy |
--- |
+/0 |
dietary factors |
high fat |
+ |
+ |
high dietary fiber |
- |
- |
high fruit/vegetable |
- |
- |
high sugar |
+ |
+ |
fast food |
+ |
+ |
vitamin D deficiency |
+ |
+ |
medications |
antibiotics |
+ |
+ |
NSAIDs |
+ |
+ |
oral contraceptives/hormone therapy |
+ |
+ |
anti-TNF-α therapy |
+ |
+ |
breastfeeding |
-/? |
-/? |
hygiene hypothesis |
pet in childhood/farm environment |
-/? |
? |
Helicobacter pylori |
- |
- |
helminthiasis |
- |
- |
measles |
? |
? |
vaccination against measles |
? |
? |
"cold chain" |
0 |
+/? |
infectious gastroenteritis in childhood |
? |
? |
urban environment |
+ |
+ |
stress |
+/? |
+/? |
”-”: decreased risk; ”+”: increased risk; ”0”: no effect; ”?”: question of debate |