Figure 1: Angiogenic privilege of cornea. [A] Normal cornea is a blood and lymphatic vessel-free tissue. Vessels are restricted only to the periphery of the cornea (limbal area). [B] In response to inflammation, this “angiogenic” privilege of the cornea can be lost leading to the ingrowth of both blood and lymphatic vessels. Micrographs from a mouse corneal micropocket model of neovascularization show pellet containing the inflammatory cytokine IL-1β robustly induces ingrowth of both new blood (CD31+LYVE1-) and lymphatic (LYVE1+CD31lo) vessels. (L: Limbus; P: Pellet).