Healthy donors Headandneck cancer Lung cancer Colorectal carcinoma Pancreatic cancer Glioblastoma Hematological malignancies
Number (n)   114 23 22 44 46 30 32
Gender (M/F)   67/47 21/2 16/6 26/18 26/20 14/16 25/7
Age Mean 42.9 62.5 66.1 64.2 69.8 56.2 41.7
  Range 20-74 36-83 48-88 29-81 44-90 25-77 19-64
  SD 14.6 12.2 10.3 13.0 40.6 14.1 12.2
  Median 41.5 61.0 66.5 67.5 73.0 59.0 42.0
lipHsp70 ELISA Mean Hsp70 (ng/ml) 6.4 12.4 16.8 11.0 14.8 67.6 11.1
  SD 2.7 6.1 16.2 5.2 7.3 37.5 9.0
ROC AUC (CI 95 %) - 0.80 0.78 0.81 0.86 0.92 0.62
  p-value - <0.0001 <0.0001 <0.0001 <0.0001 <0.0001 0.03
  Sensitivity (%) - 78 73 70 85 90 41
  Specificity (%) - 75 75 75 75 75 75
Abbreviations: AUC:Area Under the Curve; M:Male; F:Female; CI:Confidence Interval; ROC:Receiver Operating Characteristic; SD:Standard Deviation
Table 2: Age, gender and Hsp70 levels of healthy donors and patients.