Figure 4: Genomic Landscape of Colorectal Cancer. Wood, L and B. Vogelstein, Science Vol. 318, November, 2007. A two-dimensional map of genes mutated in colorectal cancers, in which a few genes "mountains" are mutated in a large proportion of tumors while most are mutated infrequently. The mutations in two individual tumors are indicated in the lower map. Note that only 3 mutations (blue dots on bottom landscape) were common to both tumors indicating a potential for weak common immunogenicity