| |
No. of Survivors/
Total No. of Animals/
Group at Following i.v.
Tumor Cell Dose |
| Treatmenta |
1 × 105 |
1 × 106 |
| None |
0/10 |
0/10 |
| (108 BCG) (108BCG) |
0/10 |
0/10 |
| (107 L10) (107 L10) |
0/10 |
0/10 |
| (107 BCG+107 L10)b |
10-Jan |
0/10 |
| (108 BCG+107 L10)b |
10-Feb |
0/10 |
| (106 BCG+107 L10) (106 BCG+107 L10) |
10-Jan |
10-Jan |
| (107 BCG+107 L10) (107 BCG+107 L10) |
10-Oct |
10-Mar |
| (108 BCG+107 L10) (108 BCG+107 L10) |
10-Oct |
10-May |
| (108 BCG+107 LVc L10) (108 BCG+107 LV L10) |
10-Jun |
10-Jan |
These experiments were terminated at 240 days after tumor injection. All non- treated controls in the 105 group died by 95 days and all non-treated controls in the 106 group died by 77 days. Significance of differences in survival was calculated by the Fisher 2-tailed exact test.
a Vaccinations were administered i.d.,6 days apart on opposite sides.
b accination was administered i.d., as a single injection.
c Low viability tumor cells. |
