Patients group Petide sequence Method Sensitivity (%) Year Reference
pSS 213-237 ELISA 0 2002 [23]
pSS 213-228 ELISA 77.5 2005 [24]
  213-228 (GST)   97    
pSS 213-237 ELISA 9 2005 [25]
sSS     14    
pSS 213-228 (GST) ELISA 90 2005 [21]
sSS     29    
pSS 514-527 BIA-core NA 2008 [15]
  228-237        
SS 1-68 ELISA 42.9 2010 [27]
  125-144   47.6    
  213-237   54.8    
  511-530   45.2    
pSS 205-220 (cyclic) ELISA 62.2 2011 [26]
  205-220 (linear)   56.1    
pSS 184-227 (GST) ELISA 75.6 2013 [20]
  506-521 (GST)   86.5    
pSS 205-221 (cyclic) ELISA 50 2014 unpublished
  520-527 (cyclic)   58.3    
pSS: primary SS; sSS: secondary SS; NA: Not Available
Table 1: Peptide-based detection of anti-M3R autoantibodies in SS patients.