Parameter Non-depressed Depressed (Mild-Moderate/Severe) p value

Number of subjects (M/F)

10 (6/4) 13 (10/3) -

Agea

53.1 (40-69) 48.5 (41-61) 0.208c

Assessment of depressionb

1.9 ± 1.29 11.2 ± 4.71 < 0.0001c*

CD4+ T cells (current) (cells/µl)b

466.5 ± 212.95 461.4 ± 252.2 0.879c
Viral load (copies/mL)a 196 (20 - 1,116) 4,616.7 (20 - 41,223) 0.624c
% undetectable 20% 26%

HCV co-infection

40% 69% 0.102d
HCV viral load (IU/mL)a 2.78 x 106 (7.93 x 104 – 5.02 x 106) 2.03 x 106 (2.84 x 105 – 6.10 x 106) 1.00c
ALT (IU/L)a 25.0 (17-36) 61.0 (7-169) 0.042c*
AST (IU/L)a 33.3 (15-51) 53.3 (13-114) 0.649c

Self-reported adherence (%)b

96.0% ± 0.02% 85.4% ± 19.5% 0.041c*

Transmission (%)

60.0% Heterosexual 53.8% Heterosexual 1.00d
aValues are expressed as mean (range)
bValues are expressed as mean ± standard deviation
cDifferences between groups were assessed with 2-sided Wilcoxon-Mann-Whitney test
dDifferences between groups were assessed with 2-sided Fisher’s Exact Test
*p < 0.05, statistically significant difference
ALT: Alanine Transaminase; AST: Aspartate Aminotransferase
Table 1: Demographic and Clinical Characteristics of HIV Positive Subjects in the Study.