Figure 3: Effects of TLR2 and TLR4 antagonists on microbicidal activity from BALB/c mice. Ex vivo effects of macrophages untreated (black bar) and stimulated with L. casei CRL 431 (grey bar), L. paracasei CNCMI-1518 (dark-grey bar) and probiotic fermented milk (light-grey bar) and them facing with TLRs antagonist. (A) Peritoneal macrophages. (B) Spleen macrophages. a,b,c,dMeans values for peritoneum and spleen macrophages without a common letter differ significantly (P<0.05). The error bars indicate standard deviations for 3 independent determinations per mouse.