| B cell Phenotype |
CD Markers |
| Total B cells |
CD19+ |
| NaïveB cells |
CD19+CD27-IgD+ |
| Mature NaïveB cells |
CD19+CD27-CD10-CD38- |
| Switched MemoryB cells |
CD19+CD27+IgD- |
| Non-switched MemoryB cells |
CD19+CD27+IgD+ |
| Double negativeB cells |
CD19+CD27-IgD- |
| T1/2B cells |
CD19+CD27-CD10+CD38+IgD+ |
| T3B cells |
CD19+CD27-CD10-CD38+IgD+ |
| Plasmablasts |
CD19DIMCD27HIGHIgD-CD38HIGH |
| PlasmaB cells |
CD19DIMCD27HIGHIgD-CD38HIGHCD138+HLA-DR+ |
| IgM+B cells |
CD19+CD27+IgD-IgM+ |
| HLA-DR+B cells |
CD19+CD27+IgD-CD38+CD138-HLA-DR+ |
| Regulatory B cells (Bregs) |
CD19+CD27LOWCD21+CD5+CD1dHIGH |
| B cell activation markers |
CD19+CD27LOWCD21+CD5+CD1dHIGHCD81+ |
| B cell receptor complex (BCR) |
CD19+CD79α+CD79β+ |
| Surface IgM |
CD19+CD79α+CD79β+IgM+ |
| Surface IgD |
CD19+CD79α+CD79β+IgD+ |
| Surface IgA |
CD19+CD79α+CD79β+IgA+ |
| Surface IgE |
CD19+CD79α+CD79β+IgE+ |
| *CD - Cluster of Differentiation, Ig - Immunoglobulin; HLA - Human Leucocyte Antigen; T1/2 - transitional 1 and 2; T3 - transitional 3. |
