| 
      
        |  | Control | HIE |  
        |  | 0- hrs | 24- hrs | 72- hrs | 0-hrs | 24- hrs | 72- hrs |  
        | S100    protein | 1.55  ±  0.42 | 1.971  ±  1.038 | 1.26  ±  0.56 | 2.45  ±  0.42* | 4.11  ±  1.26* | 2.7  ±  0.239* |  
        | IL-1 | 5.38  ±  1.35 | 6.345  ±  2.3 | 5.45  ±  1.57 | 21.26  ±  3.93* | 21.526  ±  5.35* | 11.47  ±  4.48* |  
        | IL-6 | 4.86  ±  1.6 | 7.28  ±  3.4 | 5.6  ±  2.69 | 41.8  ±  6.67a | 24.1  ±  3.78    a | 40.68  ±  6.72    a |  
        | TNFα | 10.9  ±  2.2 | 13.43  ±  3.59 | 19.51  ±  4.64 | 26.63  ±  2.75* | 24.73  ±  4.97* | 27.96  ±  5.27* |  
        | *Significant with control p<0.05, a high significant with control    P>0.001, NS non-significant with control |  |