Stage of Disease Number of cases (%) Heparanase activity in pleural fluids (% of cases) Heparanase activity in cells (% of cases)
Typical 10 (25) 40 50
Simple complicated 4 (10) 75 67
Complex complicated 3 (7.5) 100 70
Acute+chronic empyema 23 (57.5) 95 100
Table 2: Heparanase activity correlates with empyema progression.