Reagent |
Endotoxin |
Peptidoglycan |
Stimulation of Innate Immune Response |
HA* |
– |
– |
– |
rHuPH20 |
– |
– |
– |
BTH type I-S |
+ |
– |
+ |
BTH type IV-S |
+ |
– |
+ |
BTH type VI-S |
– |
+ |
+ |
Abbreviations: BTH:Bovine Testicular hyaluronidase; HA:Hyaluronic Acid; rHuPH20: Recombinant Human PH20.
*Endotoxin- and proteoglycan-free preparations of HA in various molecular weight ranges.
Adapted from Huang Z, et al. 2014 [2] |
|