NSCLC Patients (N=40) Controls (N=15) P-value
Age (years)
Mean ± SD 62.33 ± 8.08 58. 4 ± 8.26 0.178
Gender
Males 30 (75%) 9 (60%) 0.345
Females 10 (25%) 6 (40%)
Smoking
Yes 30 (75%) 8 (53.4%) 0.345
No 10 (25%) 7 (46.6%)
Mean Pack-yr
<10 19 (47.5%) 7 (46.6%) 0.355
≥ 10 21 (52.5%) 8 (53.4%)
Histopathology of NSCLC
Squamous cell carcinoma 18 (45%) - -
Adenocarcinoma 22 (55%) -
Stages of NSCLC
II 7 (17.5%) - -
III 24 (60%) -
IV 9 (22.5%) -
Objective Radiological Response
Complete response 0 - -
Partial response 20 (50%) -
No change 4 (10%) -
Progressive disease 16 (40%) -
CYFRA 21-1 level (ng/ml)
Pre-treatment level 8.13 ± 11.92 0.56 ± 0. 2 0.001
After 2 cycles of chemotherapy 7.54 ± 11.6 -
CEA level (ng/ml)
Pre-treatment level 28.26 ± 56.72 0.2 ± 0.13 0.001
After 2 cycles of chemotherapy 21.68 ± 41.77 -
Survival
Alive 26 (65%) - -
Dead 14 (35%) -
Table 2: Descriptive data recorded for the patients and the controls Data representation is in number and percentage.