Characteristics n (%) miR-205 expression Smad4 mRNA expression
Age      
≤65 23(44.2%) 0.04636 ± 0.03018 0.01468 ± 0.005275
>65 29(55.8%) 0.02214 ± 0.005835 0.01613 ± 0.002599
p value   0.2542 0.3176
Gender      
Male 35(67.3%) 0.03881 ± 0.02009 0.01737 ± 0.003710
Female 17(32.7%) 0.007869 ± 0.004414 0.02170 ± 0.004920
pvalue   0.2933 0.497
Histology      
Adenocarcinomas 23(44.2%) 0.002255 ± 0.001046 0.02318 ± 0.004031
Squamous cell carcinomas 21(40.4%) 0.06717 ± 0.03249 0.01657 ± 0.005662
Others 8(15.4%) 0.003701 ± 0.002517 0.01197 ± 0.003196
pvalue   0.0002 0.0118
Smoking status      
Yes 29(55.8%) 0.04599 ± 0.02409 0.01802 ± 0.004432
No 23(44.2%) 0.006882 ± 0.003348 0.01976 ± 0.003768
pvalue   0.1577 0.7734
Clinical stage      
I 14(26.9%) 0.02205 ± 0.01011 0.01707 ± 0.004104
II 11(21.2%) 0.005553 ± 0.003258 0.01591 ± 0.002582
III 21(40.4%) 0.01759 ± 0.008529 0.02082 ± 0.006296
IV 6(11.5%) 0.1255 ± 0.1127 0.02095 ± 0.009091
pvalue   0.7945 0.7752
Table 1: Clinicopathological parameters and expression of miR-205 and Smad4 mRNA in NSCLC tissues (mean ± SE). Date presented as mean ±
SE. Unpaired t-test for comparison of 2 groups. Kruskal-Wallis test for comparison of 3 or more groups. n: number of patients