Figure 1: Effect of melatonin [10-7M] and catecholatnines [1 μg/ml] alone and in combination on proliferation of T effector lymphocyte (Teff) showing significant increase following melatonin supplementation showing stimulatory effect of melatonin as compared to the catecholamine. Restoration significant following combined treatment of melatonin and catecholamine. Each histogram represents+SEM of 5 separate experiments. (Teffs: Teffector; MEL: Melatonin; NE: Nor-epinephrine; E: epinephrine; DA: Dopamine) ###P<0.001 vs. activated; ***P<0.001; **P<0.01 vs. Mel 10-7.