% Decrease in NKCC in CFS vs. Controls CFS Case Definition Number of Patients and Controls Studied Comments Reference
↓ 60% p<0.05 1994 CDC CFS: 10
Healthy: 10
E:T ratio=25:1,
K562=target
[39]
↓~44%a p<0.05 1994 CDC CFS: 71
Healthy: 50
E:T ratio=25:1,
K562=target
[38]
↓~ 62% Baseline p<0.05
↓~ 57% 6 months p<0.05
↓~ 83% 12 months p<0.05
1994 CDC CFS: 65
Healthy: 21
E:T ratio=25:1,
K562=target
[40]
E:T
↓~ 16%  12.5:1  NS
↓~ 27%   25:1   p<0.05
↓~ 37%   50:1   p<0.05
1994 CDC CFS: 30
Healthy: 25
3 E:T ratios were studied,
K562=target
[13]
NS=p>0.05
a~before % decrease in NKCC indicates values were obtained from data contained in Figures referenced in the text.
Table 2: Studies investigating NK cell cytotoxicity in CFS using flow cytometry assays.