Name Trial sites Immunogen Targeted immune response Efficacy References
VAX004 USA, Canada, Netherlands AIDSVAX B/B gp120 CD4+ T cells, antibodies No efficacy 5
VAX003 Thailand AIDSVAX B/E gp120 CD4+ T cells, antibodies No efficac 6
STEP Study
(HVTN502)
USA, Canada, Latin America MRKAd5 HIV-1 gag/pol/nef B CD4+ T cells, CD8+ T cells No efficacy 7
Phambili trial
(HVTN503)
SouthAfrica MRKAd5 HIV-1 gag/pol/nef B CD4+ T cells, CD8+ T cells No efficacy 8
RV144 Thailand ALVAC-HIV vCP1521 and
AIDSVAX B/E rgp120
CD4+ T cells, CD8+ T cells, antibodies 31.2% efficacy 9
Table 1: Major clinical trials of HIV vaccine.