Total cohort (n=453) Responders (n=333) Nonresponders (n=120) p
Initiation age, mean (SD) 53.4 (11.2) 52.8 (11.2) 55.2 (10.8) ns
Female n (%) 332 (73.3) 243 (72.9) 89 (74.2) ns
Relapsing-remitting, n (%) 155 (34.2) 116 (34.8) 39 (32.5)  
Primary progressive, n (%) 54 (11.9) 36 (10.8) 18 (15.0) ns
Secondary progressive, n (%) 244 (53.8) 181 (54.4) 63 (52.5)  
Disease duration, yrs, n (SD) 19.7 (10.5) 19.6 (10.4) 20.3 (10.6) ns
EDSS score, mean (SD) 5.5 (1.1) 5.5 (1.1) 5.5 (1.0) ns
EDSS: Expanded Disability Status Scale; P values reported from t-test comparisons
Table 1: Demographic and baseline clinical characteristics of patients.