Epitope Prediction Method Online Server Brief Notes (Features used in prediction method)
www.cbs.dtu.dk/services/DiscoTope/ Amino acid statistics, spatial context, surface accessibility
BEPro http://pepito.proteomics.ics.uci.edu Half sphere exposure values
Ellipro http://tools.immuneepitope.org/ellipro Protrusion index
Epitopia http://epitopia.tau.ac.il Based on Naïve Bayes classifier with physicochemical and structural geometrical properties
SEPPA http://lifecenter.sgst.cn/seppa/ Unit patch of residue triangle
Table 1: A summary of the features of some widely used B-cell epitope prediction methods. Adapted from Sun et al. [33].